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New Defender's Study Bible Notes
5:3 she which travaileth. “She which travaileth” probably refers both to Mary, the human mother of Jesus (Luke 1:31; 2:7), who “brought forth” Jesus in a stable in Bethlehem, and also to the age-long promise of the coming “seed of the woman” (Genesis 3:15) who would conquer Satan. See also Revelation 12:1-17.