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In the year that king Uzziah died I saw also the Lord sitting upon a throne, high and lifted up, and his train filled the temple.
Above it stood the seraphims: each one had six wings; with twain he covered his face, and with twain he covered his feet, and with twain he did fly.
And one cried unto another, and said, Holy, holy, holy, is the LORD of hosts: the whole earth is full of his glory.
And the posts of the door moved at the voice of him that cried, and the house was filled with smoke.
Then said I, Woe is me! for I am undone; because I am a man of unclean lips, and I dwell in the midst of a people of unclean lips: for mine eyes have seen the King, the LORD of hosts.
Then flew one of the seraphims unto me, having a live coal in his hand, which he had taken with the tongs from off the altar:
And he laid it upon my mouth, and said, Lo, this hath touched thy lips; and thine iniquity is taken away, and thy sin purged.
Also I heard the voice of the Lord, saying, Whom shall I send, and who will go for us? Then said I, Here am I; send me.
And he said, Go, and tell this people, Hear ye indeed, but understand not; and see ye indeed, but perceive not.
Make the heart of this people fat, and make their ears heavy, and shut their eyes; lest they see with their eyes, and hear with their ears, and understand with their heart, and convert, and be healed.
Then said I, Lord, how long? And he answered, Until the cities be wasted without inhabitant, and the houses without man, and the land be utterly desolate,
And the LORD have removed men far away, and there be a great forsaking in the midst of the land.
But yet in it shall be a tenth, and it shall return, and shall be eaten: as a teil tree, and as an oak, whose substance is in them, when they cast their leaves: so the holy seed shall be the substance thereof.

New Defender's Study Bible Notes

6:1 the Lord. Adonai is the divine name of God as seen in Isaiah’s vision (Isaiah 6:8,11). However, the Seraphim call Him Jehovah Sabaoth meaning “LORD of hosts” (Isaiah 6:3).


6:2 seraphims. This is the only reference in the Bible to these angelic beings, perhaps similar in rank to the cherubim, yet different in function. The name, seraphim, literally means “burners.” It is barely possible that these are the same as the cherubim.


6:3 Holy, holy, holy. The threefold ascription of holiness to the One on the throne suggests His tri-unity.


6:5 Woe is me. Isaiah had pronounced six “woes” on the people of Israel because of their sins, and justifiably so. However, when confronted with the glory and holiness of God, he must also cry: “Woe is me”—apart from the grace of God.


6:5 mine eyes have seen. Isaiah saw the Second Person of the divine Triune Godhead (John 1:18). He indeed is “the King, the LORD of hosts.”


6:9 he said. The commission given to Isaiah in Isaiah 6:9-10 is quoted by Christ (Matthew 13:13-14) as a rebuke to the religionists of His own day, who were making an outward show of religion, but had no real understanding of God and His will.


6:12 removed men far away. This prophetic warning was given some 150 years in advance of its fulfillment. The Lord always fulfills His Word, even though it may be long in coming.


6:13 it shall return. This is a reference to the “remnant,” the godly minority who would return to their land after the exile.


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